Wireless Sensor Network Optimization for Radio Tomographic Imaging

Radio tomographic imaging (RTI) is a form of device-free, passive localization (DFPL) that uses a wireless sensor network (WSN) typically made up of affordable, low-power transceivers. The intent for RTI is to have the ability to monitor a given area, localizing and tracking obstructions within. The specific advantages rendered by RTI include the ability to provide imaging, localization, and tracking where other well developed methods like optical surveillance fall short. RTI can function through optical obstructions such as smoke and even physical obstructions like walls. This provides a tool that is particularly valuable for tactical operations like emergency response and military operations in urban terrain (MOUT). Many methods to optimize the performance of RTI systems have been explored, but little work that focuses on the sequence of transceiver reports can be found in the body of literature. This thesis provides an exploration of the effects from attempting to optimize the transmission sequence in a WSN by creating a metric to quantify the value of the information a transceiver will report and using it to develop a dynamic, utility-driven, token passing process. After deriving a metric from the Fisher information matrix of the imaging solution, it was combined with a weighting based on the time each node last reported across the WSN. Modeling and simulation was performed to determine if the novel transmission sequence provided any benefit to the localization and tracking performance. The results showed a small improvement in two different localization methods when packet loss in the WSN reached 50%. These results provide a proof-of-concept that warrants further exploration and suggest that performance improvements may be realized by implementing a transmission sequence based on the metric developed in this thesis

Rationale, design, implementation, and baseline characteristics of patients in the DIG trial: A large, simple, long-term trial to evaluate the effect of digitalis on mortality in heart failure

This article provides a detailed overview of the rationale for key aspects of the protocol of the Digitalis Investigation Group (DIG) trial. It also highlights unusual aspects of the study implementation and the baseline characteristics. The DIG trial is a large, simple, international placebo-controlled trial whose primary objective is to determine the effect of digoxin on all cause mortality in patients with clinical heart failure who are in sinus rhythm and whose ejection fraction is less than or equal to 0.45. An ancillary study examines the effect in those with an ejection fraction > 0.45. Key aspects of the trial include the simplicity of the design, broad eligibility criteria, essential data collection, and inclusion of various types of centers. A total of 302 centers in the United States and Canada enrolled 7788 patients between February 1991 and September 1993. Follow-up continued until December 1995 with the results available in Spring 1996